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He continues to visit Yale Medicine every six months. He and his wife, Leah, are expecting their second child this fall. Click here to contact Yale Medicine's reproductive health and sexual medicine specialists . [3873,8726,510,2449]{"namedChunks":["modules-news-news-details-components-NewsDetails-newsDetails"]} [3873,6696,6126,2449]{"namedChunks":["modules-news-news-details-components-NewsDetails-newsDetails"]}

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12. Berner MM, Kriston L, Harms A. Efficacy of PDE-5-inhibitors for erectile dysfunction. A comparative meta-analysis of fixed-dose regimen randomized controlled trials administering the International Index of Erectile Function in broad-spectrum populations. International Journal of Impotence Research. 2006;18(3):229-235.
These diseases include high blood pressure, diabetes, clogged arteries, heart and blood vessel disease, high cholesterol, and chronic kidney disease. Other possible causes include: Nerve injury: The penis, spinal cord, prostate, bladder or pelvis may have sustained a physical injury that needs to be treated. This includes a large group of men who have had surgery or radiation treatment for prostate cancer. Unhealthy lifestyle: This includes smoking, excessive alcohol use, obesity and not exercising. Mental health: Depression, stress and anxiety surrounding sexual failure can all lead to erectile dysfunction. Medications: Some medications, including antidepressants, can cause sexual side-effects. Hormones: A small number of erectile dysfunction cases result from low levels of the male hormone testosterone. .

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The information on Drugwatch.com has been medically and legally reviewed by more than 30 expert contributors, including doctors, pharmacists, lawyers, patient advocates and other health care professionals. Our writers are members of professional associations, including American Medical Writers Association, American Bar Association, The Alliance of Professional Health Advocates and International Society for Medical Publication Professionals. Assisting patients and their families since 2008. Helped more than 12,000 people find legal help. A+ rating from the Better Business Bureau. 5-star reviewed medical and legal information site.
Though erections may seem straightforward, the science behind them is complicated. At a basic level, erections happen thanks to a balance of blood flow into and out of the penis. When vascular, hormonal, nerve, or other physical or psychological changes disrupt blood flow, it’s harder to get and keep erections.

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Sildenafil (sildenafil citrate) is prescription medicine used to treat erectile dysfunction (ED).
Sound waves directed at the penis and surrounding tissues stimulate blood flow, cellular growth and generation of new, healthy blood vessels (neovascularization). Studies show that acoustic (sound) wave therapy such as pulse therapy also provides long-term improvement of physiological mechanisms involved in erections. No side effects have been reported by men using pulse therapy for ED.5

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Some men take supplements or try other forms of alternative medicine to treat their ED.

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The data collectors were given 1 day of training on the purpose of the study and the data collection procedures. A pretest was carried out on 5 sildenafil users that came to two randomly selected pharmacies in the town. Based on the results, modifications (removal of questions that were not feasible in the current setup and/or re-writing of the wordings in simpler forms) were applied to the questionnaire and those participants in the pretest were excluded from the final study. The collected data were checked for completeness and consistency each day before entering into the software for analysis.

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    Sildenafil is not suitable for some people. To make sure it's safe for you, speak to your doctor or pharmacist before taking sildenafil if you:

    Red ginseng, also known as panax ginseng, is a great option for improving blood flow and opening up the arteries that supply blood for erections. Researchers reviewed seven studies relating to the use of red ginseng to remedy ED in 2008. These studies concluded that there was “suggestive evidence towards the effectiveness of red ginseng in the treatment of erectile dysfunction.”
    If you smoke, talk to your doctor about quitting and whether prescription aids can help you.

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    The Department of Urology brings together the best of patient care, education and research. Urology Research

    Rarely, sudden decreased vision, including permanent blindness, in one or both eyes (NAION) may occur. If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke.
    Men who have ED should not ignore the ailment. After all, more than 40 percent of men over the age of 40 struggle with ED. Men struggling with ED should talk to their doctor about potential causes and treatment options, as well as make lifestyle changes to reduce incidence. Young men should take preventive steps, including the development of healthy lifestyle habits, like eating a balanced diet and maintaining a healthy weight, which can reduce their risk of ED.

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    Drugwatch.com writers follow rigorous sourcing guidelines and cite only trustworthy sources of information, including peer-reviewed journals, court records, academic organizations, highly regarded nonprofit organizations, government reports and interviews with qualified experts. Review our editorial policy to learn more about our process for producing accurate, current and balanced content. Berman, L. (2014, June 25). The truth about erectile dysfunction. Retrieved from: https://www.foxnews.com/health/the-truth-about-erectile-dysfunction Brophy Marcus, M. (2016, March 10). First generic version of Viagra approved by FDA. Retrieved from: https://www.cbsnews.com/news/first-generic-drug-for-viagra-called-sildenafil-citrate-approved-by-fda/ FDA. (2012, August 30). FDA Drug Safety Communication: FDA recommends against use of Revatio (sildenafil) in children with pulmonary hypertension. Retrieved from: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-recommends-against-use-revatio-sildenafil-children-pulmonary FDA. (2014, March 31). FDA Drug Safety Communication: FDA clarifies Warning about Pediatric Use of Revatio (sildenafil) for Pulmonary Arterial Hypertension. Retrieved from: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-clarifies-warning-about-pediatric-use-revatio-sildenafil-pulmonary FDA. (2018). Full Prescribing Information: Revatio (sildenafil). Retrieved from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021845s018lbl.pdf FDA. (2017). Viagra – sildenafil citrate tablet, film coated: Full Prescribing Information. Retrieved from: http://labeling.pfizer.com/ShowLabeling.aspx?id=652 Brigham Health. (2020). Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Retrieved from: https://www.brighamandwomens.org/neurology/neuro-ophthalmology/non-arteritic-anterior-ischemic-optic-neuropathy Heid, M. (2014, October 28). The Truth about Erectile Dysfunction. Retrieved from: https://www.menshealth.com/health/a19521004/rising-erectile-dysfunction-rates/ History.com, A&E Television Networks, LLC. (2019, July 28). 1998: FDA approves Viagra. Retrieved from: http://www.history.com/this-day-in-history/fda-approves-viagra Li, W., Qureshi, A. A., Robinson, K. C., et al. (2014). Sildenafil Use and Increased Risk of Incident Melanoma in US Men: A Prospective Cohort Study. Retrieved from: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1857095 MedlinePlus, NIH. (2018, January 15). Sildenafil. Retrieved from: https://medlineplus.gov/druginfo/meds/a699015.html MedlinePlus, NIH. (2016, August 24). Sexual Problems in Men. Retrieved from: https://medlineplus.gov/sexualproblemsinmen.html MedlinePlus, NIH. (2017, January 3). Erectile Dysfunction. Retrieved from: https://medlineplus.gov/erectiledysfunction.html NIH. (2017). Erectile Dysfunction. Retrieved from: https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction NIH. (2016). Pulmonary arterial hypertension. Retrieved from: https://medlineplus.gov/genetics/condition/pulmonary-arterial-hypertension/ Pendick, D. (2014, June 5). Erectile dysfunction drugs and skin cancer – should you worry? Retrieved from: https://www.health.harvard.edu/blog/erectile-dysfunction-drugs-skin-cancer-worry-201406057197 Panchatsharam, P. K., & Zito, P. M. (2019, April 21). Physiology, Erection. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK513278/ Loeb, S. et al. (2015). Use of Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Risk of Malignant Melanoma. Retrieved from: https://jamanetwork.com/journals/jama/fullarticle/2338254 Pottegård, A. et al. (2016). Use of sildenafil or other phosphodiesterase inhibitors and risk of melanoma. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046205/. Wang, J. Z. et al. (2019). No Causal Link between Phosphodiesterase Type 5 Inhibition and Melanoma. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704303/

    Average mean (diastolic+one third difference in systolic and diastolic pressure) lying (ly), sitting (si), and standing (st) blood pressures in 10 patients with Parkinson's disease who tolerated the medication with minimal effect on the blood pressures (top panel); three patients with multiple system atrophy who tolerated the medication without an adverse effect on their blood pressures (middle panel); and three patients who developed a symptomatic fall in their blood pressures 1 hour after treatment with Sildenafil (bottom panel).
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    Red ginseng is considered the “herbal Viagra” and is great in improving erections and increases a man’s libido. The red ginseng is got from steaming the ginseng root and then drying it. The ginseng root is the most effective part of the plant and can be taken as a supplement too. For maximum efficiency, take ginseng in dosages between 600 to 1,000mg three times a day. You’ll see your ED start to reduce.

    Treatment options for ED have evolved considerably over the past decade to encompass psychological counseling; oral, topical, intraurethral, and intracavernosal vasoactive therapy; oral therapies with other or unknown mechanisms; hormone replacement; vacuum constriction devices; and surgery, including vascular bypass procedures and penile implants. The goal of treatment is to restore satisfactory erections with minimal adverse effects. Men have demonstrated a strong preference for oral treatments even if they have low efficacy.
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Beck RO, Betts CD, Fowler CJ (1994) Genito-urinary dysfunction in multiple system atrophy: clinical features and treatment in 62 cases. J Urol 151:1336–1341.

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You’ll need to take this medication 30-60 minutes before sex. If you try BlueChew (a chewable form of sildenafil), you’ll discover whether you are one of the many men who find that the chewable form takes effect much quicker, which would mean you only have to take it a half hour in advance. Now is a great time to try it because BlueChew lets our readers enjoy a free month of treatment to see if it works for you.

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