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Many recreational drugs can lead to erection trouble. Both uppers (like cocaine and amphetamines) and downers (like marijuana and opiates) may cause problems. These drugs often slow down your central nervous system, and some can also damage blood vessels. If you think you have a drug problem, this is just one more reason to seek help.
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. .

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Singer C, Weiner WJ, Sanchez-Ramos JR, et al. (1989) Sexual dysfunction in men with Parkinson's disease. Journal of Neurological Rehabilitation 3:199–204.
In patients who either fail to respond to first or second-line therapy, or are not interested in the conservative therapies, penile prosthesis implantation is available. Malleable and rigid implants were available for many years, but in 1973 the world of penile prosthetics took a giant leap forward with the advent of the inflatable penile implant. Most implants done nowadays are of the inflatable variety. Adverse events including malfunction and infection are rare, and patient satisfaction is very high.45

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If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include severe dizziness, fainting, painful/prolonged erection.
National Kidney and Urologic Diseases Information Clearinghouse: "Erectile Dysfunction."

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This is why a healthy circulatory system is key to maintaining penile health. In addition, stress causes nerve endings to be less receptive to incoming signals, making erection difficult.

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First line treatment will be medication with a phosphodiesterase inhibitor such as sildenafil (Viagra), tadalafil (Cialis) or avanafil (Spedra). These drugs only work when used together with sexual stimulation and will have no effect on your sex drive. There is no evidence that these drugs are dangerous if you have underlying heart disease. However, they should not be used if you are taking nitrates (e.g. GTN, isosorbide) for angina

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    Many men find relief through a combination of these treatments. Your doctor will help you decide the fastest and best method for curing your erectile dysfunction. QUESTION Testosterone is a chemical found only in men. See Answer

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    When VIAGRA 100 mg oral was co-administered with amlodipine, 5 mg or 10 mg oral, to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic.
    Do It AtHome: Take 15 grams of the dried roots ofasparagus and boil it with one cup of milk. Take this mixture twice daily forsatisfactory results. The regular use of this recipe is valuable to cureimpotency and premature ejaculation.

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    At visit 1, consent was obtained before demographic data and screening blood samples were taken. Patients were advised to stop all therapy for erectile dysfunction and sexual activity was encouraged.

    If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.
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    Other tests, if indicated, are normally arranged by the urology specialist clinic and will be discussed with you.

    The results from this pilot study are shown in Table 3; the mean resting systolic and diastolic blood pressures decreased by 7% and 10% compared to baseline in these patients. Mean resting values for right atrial pressure, pulmonary artery pressure, pulmonary artery occluded pressure and cardiac output decreased by 28%, 28%, 20% and 7% respectively. Even though this total dosage produced plasma sildenafil concentrations which were approximately 2 to 5 times higher than the mean maximum plasma concentrations following a single oral dose of 100 mg in healthy male volunteers, the hemodynamic response to exercise was preserved in these patients.
    Taking a supplement of this amino acid can help increase blood flow both to the penis and the heart, Harry Fisch, MD, FACS, a clinical professor of urology and reproductive medicine at Weill Cornell Medical College/New York Presbyterian Hospital, tells Yahoo Health. While there’s no medical guarantee it will work like Viagra, L-arginine is known to increase levels of nitric oxide, a gas that relaxes muscles and increases blood flow, and is involved in maintaining an erection.

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If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. atazanavir cobicistat elvitegravir/cobicistat/emtricitabine/tenofovir DF isosorbide dinitrate isosorbide mononitrate nelfinavir nitroglycerin IV nitroglycerin PO nitroglycerin rectal nitroglycerin sublingual nitroglycerin topical nitroglycerin transdermal nitroglycerin translingual ombitasvir/paritaprevir/ritonavir ombitasvir/paritaprevir/ritonavir and dasabuvir riociguat

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It is likely to improve ED management and benefit a large number of men, particularly in terms of recognising ED as a sentinel of vascular disease.

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No evidence of teratogenicity, embryotoxicity or fetotoxicity was observed in rats and rabbits which received up to 200 mg/kg/day during organogenesis. These doses represent, respectively, about 20 and 40 times the Maximum Recommended Human Dose (MRHD) on a mg/m² basis in a 50 kg subject. In the rat pre-and postnatal development study, the no observed adverse effect dose was 30 mg/kg/day given for 36 days. In the nonpregnant rat the AUC at this dose was about 20 times human AUC.

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