All authors had contributed to the data analysis, drafting, or revising the article. They gave the final approval of the manuscript to be published and agreed to be accountable for all aspects of the work.
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We don't currently post comments online but are always keen to hear your feedback. References Map of Medicine - Erectile Dysfunction Pathways NHS - Erectile Dysfunction British Society for Sexual Medicine - Management Guidelines fo Erectile Dysfunction Patient UK - Erectile Dysfunction
Arginine: It's found naturally in food, and it relaxes blood vessels and is used to treat heart problems. Doctors think it boosts circulation to the penis, but Espinosa says he doesn’t recommend it much because the body metabolizes it so quickly. “You need a lot and you need to take it frequently for it to work,” he says.
Other side effects associated with the use of sildenafil may include diarrhea, heartburn, difficulty falling asleep or staying asleep, numbness, burning or tingling in the arms, hands, feet or legs, nosebleeds, and sensitivity to light.
Did you know that certain medical condition may be responsible for ED? Some causes of impotence are medically treatable and reversible. Learn more about what can be done about erectile dysfunction with the Impotence Quiz.
Over time, your best value will depend a little on the conclusions from your doctor’s consultation. They might think a 45mg dose may be just right for you, and a company like BlueChew offers precisely that. So, even if you can get a better deal on a 40mg dose elsewhere, it may not be as effective. However, different dosage needs – for instance, if you only need 20mg doses of sildenafil – or a desire to use a different medication like Stendra instead might mean a company like Roman or Hims offers better value for you.
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Based on testing and examination of studies and evidence, we believe you may find an effective treatment for mild or moderate ED using a natural supplement. As with any medication or supplement, it’s imperative to discuss this with your primary care provider to make sure there’s nothing in your medical history that might make these alternative treatments unsafe for you.
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One randomized, double-blind, placebo-controlled, crossover, flexible-dose (up to 100 mg) study of patients with erectile dysfunction resulting from spinal cord injury (n=178) was conducted. The changes from baseline in scoring on the two end point questions (frequency of successful penetration during sexual activity and maintenance of erections after penetration) were highly statistically significantly in favor of VIAGRA. On a global improvement question, 83% of patients reported improved erections on VIAGRA versus 12% on placebo. Diary data indicated that on VIAGRA, 59% of attempts at sexual intercourse were successful compared to 13% on placebo.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure), stroke in the past 6 months, kidney disease, liver disease, high or low blood pressure, dehydration, penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease), history of painful/prolonged erection (priapism), conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma), eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION).
In addition, heart attack, stroke, irregular heartbeats and death have happened rarely in men taking VIAGRA. Most, but not all, of these men had heart problems before taking VIAGRA. It is not known if VIAGRA caused these problems.
The production of testosterone and other hormones naturally decreases with age, and this can disrupt erections. Also, in rare instances, kidney failure and liver disease may throw off the balance of hormones necessary for proper erection and intercourse. In most cases, testosterone replacement therapy can bring levels of the hormone back to normal.
Overall the baseline and 10 week postplacebo data for IIEF (questions 3 and 4) and the QoL for whole life and sex life were similar. The same responses after 10 weeks of active medication starting with 50 mg and titrated up to 100 mg in most patients showed a marked and significant improvement in being able to obtain (question 3) and maintain an erection (question 4) for sexual intercourse. Although there was little change in the whole life QoL there was a marked improvement in sex life (table 1). The partner questionnaire response confirmed the improvement. There were no serious adverse events over the study period. One patient reported headache and a warm feeling after taking the active medication but did not discontinue it.
Reports of dangers from ED drug abuse run the gamut from unsafe sex practices and a heightened sexually transmitted infection (STI) risk to fatal drug interactions. They include these specifics:
More body fat/less muscle massMild anemia caused by decreased hemoglobinOnset of osteoporosisLoss of hairFatigue/less energyReduced sex driveDepression/moodiness/cognitive problems