Viagra is the brand name of the prescription medicine sildenafil. It’s used to treat erectile dysfunction (trouble getting or keeping an erection) in men.
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The pathogenesis of organic ED is related to dysfunction of the endothelium. Endothelial cells can become injured through a variety of mechanisms, most of which cause oxidative stress on the tissues. Many of these causes of oxidative stress are related to lifestyle issues which lead to hypertension, diabetes and dyslipidaemia (figure 1). Endothelial cell dysfunction results in reduction of endothelium-dependent vasorelaxation as well as increased adhesion of leukocytes to the endothelium. Endothelial cell injury then leads to a variety of sequelae, including ED, other types of vasoconstriction, atherosclerosis and thrombus formation.18
If you use any of these medications and start to have erection problems, don't just stop taking them on your own. Talk to your doctor about possible fixes.
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The patient's partner was also given a brief questionnaire to complete independently.
Erectile dysfunction is the inability to achieve or maintain an erection that is sufficiently rigid for sexual intercourse. Sexual drive and the ability to have an orgasm are not necessarily affected. Because all men have erection problems from time to time, doctors diagnose erectile dysfunction if a man fails to maintain an erection satisfactory for intercourse on at least 25% of attempts. Worldwide, erectile dysfunction occurs in close to 20% of men.
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12. Berner MM, Kriston L, Harms A. Efficacy of PDE-5-inhibitors for erectile dysfunction. A comparative meta-analysis of fixed-dose regimen randomized controlled trials administering the International Index of Erectile Function in broad-spectrum populations. International Journal of Impotence Research. 2006;18(3):229-235.
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Also, men who have a chronic vitamin B12 deficiency and eat more processed meats and refined grains are more likely to develop ED.
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The tests performed will be left to your doctor's discretion. It is common to measure kidney function, liver function, cholesterol, as well as checking your blood cells for anaemia or other problems. A fasting blood sugar measurement will be performed to exclude diabetes. A PSA (prostate specific antigen) blood test may also be carried out if necessary.
It's common for ejaculation problems to occur as you age. Ejaculation problems usually don’t pose health concerns, but they can be embarrassing to experience. Learn how to fix ejaculation problems and talk to your doctor.
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Erectile dysfunction is a very common condition for aging men, but is it a normal part of the aging process? Though it’s a sensitive topic, it's important to discuss any signs of erectile dysfunction with your doctor -- especially because erectile dysfunction is sometimes the first sign of underlying health conditions such as cardiovascular problems.
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A study published in May 2014 in The Journal of Sexual Medicine found that some men can reverse erectile dysfunction with healthy lifestyle changes, such as exercise, weight loss, a varied diet, and good sleep. The Australian researchers also showed that even if erectile dysfunction medication is required, it's likely to be more effective if you implement these healthy lifestyle changes.
The doctor or nurse will ask about your lifestyle and relationships, and any problems you might be having.
The most common side effects of Sildenafil: headache; flushing; upset stomach; abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision; stuffy or runny nose; back pain; muscle pain; nausea; dizziness; rash.
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The use of VIAGRA offers no protection against sexually transmitted diseases. Counseling of patients about the protective measures necessary to guard against sexually transmitted diseases, including the Human Immunodeficiency Virus (HIV), may be considered.
For an algorithm to facilitate evaluation and treatment of patients with ED, see figure 2.
More frequent EDM use was associated with decreased erectile confidence, which in turn showed negative relations with erectile function. Men who use EDMs for recreational purposes may be at increased risk of becoming psychologically dependent, which in turn could lead to psychogenic-based ED symptoms (14).
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ED pills, PDE-5 inhibitors that are prescription medication, have been clinically proven to effectively treat erectile dysfunction. If you’re curious whether ED medication might be right for you, you can take the K Health assessment and chat with a K Health doctor about potentially getting a prescription. How does K Health treat ED?
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Dehydroepiandrosterone (DHEA)L-arginineGinsengPropionyl-L-carnitineYohimbeGinkgoHorny goat weed (epimedium)ZincAcupuncture and Erectile Dysfunction
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Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a man get and keep an erection.
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But the advantages of exercise may be lower in men who have heart disease or other underlying medical conditions.
heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;vision changes or sudden vision loss; orerection is painful or lasts longer than 4 hours (prolonged erection can damage the penis).
In 2012, the U.S. Food and Drug Administration (FDA) advised that Revatio (sildenafil) should not be prescribed to children ages 1 through 17 for pulmonary arterial hypertension (PAH), or high blood pressure in the blood vessels leading to the lungs. This recommendation came after a long-term pediatric clinical trial that showed that children taking a high dose of Revatio had a higher risk of death than children taking low doses, and that the lower doses of Revatio were not effective in improving exercise ability in children.
Erectile dysfunction is said to be psychological and this can be influenced by cases acquainted with the following:
Do It AtHome: Pounded and mixed with almonds,pistachio nuts, and quince seeds in equal quantities, about 100 gm of drieddates should be taken daily foe excellent results.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
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Drinking and sex aren't always a great mix. More than a drink or two can dampen your libido, soften your erection, or make it difficult to have an orgasm. If alcohol is causing your ED, it probably will go away when you cut back on or quit drinking.
Inhibition of the PDE-5 enzyme increases the concentration of a signaling molecule known as cyclic guanosine monophosphate (cGMP), which leads to relaxation of vascular smooth muscles, dilation of blood vessels, and improved blood flow.
Simply walking may be a good activity to try. According to one study, 30 minutes of walking a day was associated with a 41 percent decrease in risk for ED.
There are no controlled clinical data on the safety or efficacy of VIAGRA in the following groups; if prescribed, this should be done with caution. Patients who have suffered a myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months; Patients with resting hypotension (BP < 90/50 mmHg) or hypertension (BP > 170/110 mmHg); Patients with cardiac failure or coronary artery disease causing unstable angina. Prolonged Erection And Priapism
Platelet-Rich Plasma, or PRP, is plasma that is found in your blood that has many healing properties. PRP is the latest nonsurgical procedure that utilizes plasma cells of the blood to cure erectile dysfunction. It is one of the effective and safest ways to treat erectile dysfunction. It is also called as P-shots. It causes firm and stronger erections It improves sexual stamina and better erection Increased penile length and girth Improvement in or the resolution of penile curvature Resolution of penile pain with erection Improved sensitivity in the penis Improves overall blood flow to the penis Can I reverse my Erectile Dysfunction?
“The arteries in the penis are the smallest, so we can see the beginning of arterial hardening and heart disease in the penis before we see it in the coronary arteries or the heart,” Dr. Walker says. “So if you’re a younger man who is going to have a heart attack in your 50s or 60s, we’re going to see it in the penis first.”
Start your review of Erectile Dysfunction Cure: How To Cure ED Naturally & Quickly & Enjoy Your Intimate Life (Jelqing, Male Enhancement, ED Cure, Erectile Dysfunction, Infertility) Tim Hansen rated it really liked it Antonio Rivera rated it liked it Mayank Agarwal rated it it was amazing Jerry Brija rated it really liked it Deb Leonard rated it it was amazing David Cox rated it really liked it James W. Martin is currently reading it Alfonso Bodden is currently reading it Thomas Blakeslee marked it as to-read victoria magagna is currently reading it Ernest Allen is currently reading it Shawn Winston is currently reading it Narayan Naik is currently reading it Iscritto Iscritti marked it as to-read Marina H Shojinaga is currently reading it The common problem of "too many books, too little time" can reach truly dire proportions when you work on the Goodreads editorial team. After... Company About us Careers Terms Privacy Interest Based Ads Ad Preferences Help
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This medicine is available on prescription and you can also buy it from most pharmacies. It comes as standard tablets, chewable tablets, and as a liquid that you swallow. Who can take sildenafil
Pfizer saw an economical advantage with this new discovery and experienced immediate success with Viagra, accumulating about a billion dollars in sales in its first year alone. In 2014, Fox News reported that “over 30 million men suffer from erectile dysfunction,” and it is estimated that approximately 20 million Americans have taken Viagra. Men’s Health reported around the same time that during the last two or three decades, ED rates have gone up, especially among younger men. The Journal of Sexual Medicine published results from one study that showed that “one out of every four new ED patients is under 40 years old.”
Unfortunately, people who take nitrates for cardiovascular conditions may not be suitable candidates for PDE-5 inhibitor ED treatments. They will likely have to pursue alternative ED treatments.
Co-administration of ritonavir, a strong CYP3A4 inhibitor, greatly increased the systemic exposure of sildenafil (11-fold increase in AUC). It is therefore recommended not to exceed a maximum single dose of 25 mg of VIAGRA in a 48 hour period [see DOSAGE AND ADMINISTRATION, WARNINGS AND PRECAUTIONS, CLINICAL PHARMACOLOGY].
Some over-the-counter (OTC) supplements may help increase blood flow to the penis and mitigate the symptoms of ED. Keep in mind that because the FDA doesn’t monitor or approve these supplements, you may not get a consistent dose. Additionally, the supplements may not always contain the ingredient advertised, or they may contain other unlisted ingredients. Ginseng: A small number of studies suggests that red ginseng, or Korean red ginseng, may increase penile blood flow and help treat ED. L-arginine: Some men with ED appear to have low levels of this amino acid. When combined with tadalafil (Cialis) or pycnogenol (a compound found in pine bark), it may help improve ED, but more research is necessary because the studies have been small.Horny goat weed: This herb has long been used in traditional Chinese medicine in the treatment of ED and sexual dysfunction. However, one study from 2017 found that while there is some evidence that it helps increase sexual activity in castrated rats, there is little to no direct evidence it increases penile blood flow in human males. Stretches
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The Asian Journal of Andrology notes that foods that are rich in fat or otherwise calorically dense can contribute to lowered sexual activity. This study recommends a “Mediterranean-style diet,” which consists primarily of whole-grain foods, fruits, vegetables, full-dairy products, and legumes. Meat lovers may be disappointed to see that eating habits that limit the consumption of red meat are recommended to improve heart health. This diet is designed to reduce bodily inflammation and a lower risk of coronary disease. In short, eating healthy is pivotal to boosting penile function and sexual stamina, and can be an effective natural remedy for ED.
In another study in healthy male volunteers, co-administration with the HIV protease inhibitor ritonavir, which is a highly potent P450 inhibitor, at steady state (500 mg bid) with VIAGRA (100 mg single dose) resulted in a 300% (4-fold) increase in sildenafil Cmax and a 1000% (11-fold) increase in sildenafil plasma AUC. At 24 hours the plasma levels of sildenafil were still approximately 200 ng/mL, compared to approximately 5 ng/mL when sildenafil was dosed alone. This is consistent with ritonavir's marked effects on a broad range of P450 substrates. VIAGRA had no effect on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].
Overall the baseline and 10 week postplacebo data for IIEF (questions 3 and 4) and the QoL for whole life and sex life were similar. The same responses after 10 weeks of active medication starting with 50 mg and titrated up to 100 mg in most patients showed a marked and significant improvement in being able to obtain (question 3) and maintain an erection (question 4) for sexual intercourse. Although there was little change in the whole life QoL there was a marked improvement in sex life (table 1). The partner questionnaire response confirmed the improvement. There were no serious adverse events over the study period. One patient reported headache and a warm feeling after taking the active medication but did not discontinue it.
A German study found that 69% of men involved in a sleep apnea study also suffered from ED. Disruptions to breathing during sleep affect oxygen levels in the blood, which can cause problems generating an erection. Lack of sleep also disrupts hormone production.
Do not take VIAGRA if you take medicines called guanylate cyclase stimulators which include: Riociguat (Adempas®) a medicine that treats pulmonary arterial hypertension and chronicthromboembolic pulmonary hypertension.
Health Topics Symptoms and Signs Supplements Medications Slideshows Images Quizzes What Is the Fastest Way to Cure Erectile Dysfunction? Medical Author: Shaziya Allarakha, MD Medical Reviewer: Pallavi Suyog Uttekar, MD Causes What Causes Erectile Dysfunction? Is it Normal? Is ED a Normal Part of Aging? 6 Treatment Methods 6 Ways to Treat Erectile Dysfunction Guide What Is the Fastest Way to Cure Erectile Dysfunction? Topic Guide Treatment of erectile dysfunction depends on the underlying cause of the condition. Learn about 6 treatment methods
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Low-intensity extracorporeal shock wave therapy is considered investigational. The benefits do not outweigh the risks. There is only a small amount of evidence that it works for the short term and little evidence that normal erectile function returns after treatment..
Table 1: Adverse Reactions Reported by ≥ 2% of Patients Treated with VIAGRA and More Frequent than Placebo in Fixed-Dose Phase II/III Studies (n=607) Headache 16% 21% 28% 7% Flushing 10% 19% 18% 2% Dyspepsia 3% 9% 17% 2% Abnormal vision† 1% 2% 11% 1% Nasal congestion 4% 4% 9% 2% Back pain 3% 4% 4% 2% Myalgia 2% 2% 4% 1% Nausea 2% 3% 3% 1% Dizziness 3% 4% 3% 2% Rash 1% 2% 3% 1% †Abnormal Vision: Mild to moderate in severity and transient, predominantly color tinge to vision, but also increased sensitivity to light, or blurred vision.
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Mayo Clinic: "Erectile dysfunction," "Erectile dysfunction and diabetes: Take control today," "High blood pressure and sex: Overcome the challenges," "High Cholesterol," "Performance-enhancing drugs: Know the risks."
Erectile dysfunction can be a mystery, with no clear-cut cause. It can have vascular, neural, hormonal, and psychological components, depending on the man. Pharmacies sell a little blue pill that can help with performance, but sometimes you don’t want to rely on a drug — you want to find a natural “cure,” something that doesn’t shout “erectile dysfunction” when found in the medicine cabinet.
In recent years, the FDA has seized many over-the-counter products for male sex problems because they contained dangerous or undeclared ingredients. Lab tests have discovered these risky ingredients in nearly 300 products.
This is why a healthy circulatory system is key to maintaining penile health. In addition, stress causes nerve endings to be less receptive to incoming signals, making erection difficult.
It is recommended that prior to proceeding with other therapies, patients reporting failure of their PDE5 inhibitors should be evaluated to determine whether the trial was adequate. This would include discussion of fatty food ingestion, which is important with sildenafil, and specific patient population such as prostatectomy and diabetes. Furthermore, patients should be encouraged to continue attempts at intercourse up to the eighth to tenth dose of PDE5 inhibitor as improvements in success rate are seen up to the eighth to tenth dose.
Sildenafil is not suitable for some people. To make sure it's safe for you, speak to your doctor or pharmacist before taking sildenafil if you:
In addition, a study published in the Journal of Sex and Marital Therapy showed that the use of L-arginine and pycnogenol supplement helped a number of men ages 25 to 45 years old. The ED sufferers achieve normal erections without any side effects.
Type “natural ED cures” into your favorite search engine and you’ll pull up a bevy of herbs and natural remedies that supposedly help. But are they safe, and do they actually work?
Natural Erectile Dysfunction Remedy, with no need for drugs regularly that may have some very serious side effects and headaches.
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Do you know about all the serious issues with Viagra and their generic substitutes? Check out how a lot of informed men are able to regain full function without pills, shots, or surgery and go back to being intimate the natural way.
