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Sildenafil is also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs).

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The HIV drug ritonavir, when taken with Viagra, resulted in a four-fold increase in the amount of sildenafil present in patients’ blood in clinical studies. This necessitated a recommended dosing adjustment in patients taking Viagra while also being treated with ritonavir. Patients taking both medications should not take Viagra more often than every 48 hours. Are also taking medicines called nitrates (such as nitroglycerin), which are used to treat high blood pressure during surgery and certain heart conditions Use street drugs called “poppers” (such as amyl nitrate or amyl nitrite, and butyl nitrate) Take any medicines called guanylate cyclase stimulators, such as riociguat (Adempas), which are used to treat two types of pulmonary hypertension in adults Have had allergic reactions to sildenafil, as contained in Viagra and Revatio, or any other ingredients in Viagra Please seek the advice of a medical professional before making health care decisions. Share This Page: Share this page on Twitter Share this page on Facebook Copy Link Share This Page: https://www.drugwatch.com/viagra/ Copy Link TELL US WHAT YOU THINK Did You Find Drugwatch Helpful? Thank you for your feedback. Do you have any thoughts you'd like to share about Drugwatch.com? This article contains incorrect information This article doesn't have the information I'm looking for Send Your Message
Alprostadil is an FDA-approved erectile dysfunction drug that can be injected directly into the penis to trigger an automatic erection. "Penile injection is the most effective type of ED treatment for men who can't take oral treatment," says Nelson Bennett, MD, a urologist at the Lahey Clinic in Burlington, Mass. In fact, it has an 85 percent success rate. Possible side effects include a burning sensation and priapism, an erection that lasts more than four hours and requires medical treatment. .

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Mindy Kaling, 43 says she didn't know she was 'unattractive until I was the star of my own show’
Drugs & Vitamins Drugs A-Z Generic Drugs A-Z Drugs by Classification Drugs Comparison (Drug Vs. Drug) Vitamins & Supplements Drug Interaction Checker Pill Identifier Tools & Resources Diseases & Conditions Medical Dictionary Viagra Generic Name: sildenafil citrate Brand Name: Viagra Drug Class: PAH, PDE-5 Inhibitors, Phosphodiesterase-5 Enzyme Inhibitors Medical Reviewer: John P. Cunha, DO, FACOEP Last updated on RxList: 7/20/2022 home drugs a-z list side effects drug center viagra (sildenafil citrate) drug Side Effects Center Related Drugs Androderm Caverject Impulse Cialis Levitra Staxyn Stendra Testim Uptravi Viagra User Reviews Drug Description Indications & Dosage Side Effects Drug Interactions Warnings & Precautions Overdose & Contraindications Clinical Pharmacology Medication Guide

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If you have erectile dysfunction, you may be prescribed Viagra. However, what happens if that medication doesn’t work? The good news is that there are many options for treating erectile dysfunction. Let’s explore what Viagra is, why it may or may not work, and what to do if this treatment doesn’t improve your erections.
Although other issues such as nerve damage and hormone abnormalities can also lead to erectile dysfunction, the failure of the blood vessels to dilate properly is one of the more common causes, Wittert said. "This is an early abnormality in the pathway to more serious heart disease."

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The first stem cell study for the treatment of ED was published in 2004. This study used embryonic stem cells to treat ED. At this time, there is a total of 36 published basic studies assessing stem cell therapy for ED, with two clinical trials. The mechanism of action of stem cells is to generate angiogenesis with subsequent increase in cavernosal smooth muscle cells within the corporal bodies.46

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    Tags: elderly, erectile dysfunction, impotence, male, Men's Health, older adults, senior

    Living Alone and Having Multiple Breakups Are Associated With Higher Chronic Inflammation in Men, but Not in Women Call 443-232-1077
    You can buy sildenafil (Viagra) over the internet. Be very careful if you do this as many websites sell fake medicines.

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    You shouldn’t use these medicines if you take nitroglycerin or any other nitrates for chest pain. If you have heart problems, tell your doctor before taking any ED medicines. These medicines can have serious side effects in people who have heart problems.

    In studies, tadalafil is a top choice among couples -- we believe it will be best for most people. Plus, BlueChew offers our readers an exclusive opportunity to try BlueChew ED treatment for a free month! Just use the links on this page in order to access your free trial.
    It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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    Though they rely on the same primary mechanism to treat ED, research confirms that these different PDE-5 inhibitors tend to produce side effects to various degrees. For instance, a slightly higher percentage of people who take sildenafil (and Viagra) report unwanted vision changes, while a slightly higher percentage of tadalafil (and Cialis) users report muscle pain. All in all, most men barely notice any side effects.

    Before we get into why it might not work for you, let’s discuss how Viagra actually works. Viagra is the brand name for the drug sildenafil, which is a PDE5 inhibitor. PDE5 is an enzyme that can make it difficult for your blood vessels and arteries to relax and dilate. This can reduce the amount of blood flow to various parts of the body, including the penis. PDE5 inhibitors reduce the amount of the PDE5 enzyme in your body to increase blood flow for your erections. Therefore, sildenafil and other PDE5 inhibitors address blood flow problems that may cause erectile dysfunction.
    Impotence treatments were discussed in the oldest Chinese text, The Yellow Emperor’s Classic of Internal Medicine, which describes traditional Chinese medicine during the time of the Yellow Emperor’s rule which ended around 2600 BC. One of the treatments for impotence discussed is a potion with 22 ingredients.4

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    Benign Prostatic Hyperplasia/BPH, Energy Wave Therapy, Erectile Dysfunction, General Urology, Hypospadias, Kidney Stones, Penile Prosthesis, Urethral Fistula, Urethral Stricture Disease, Urinary Incontinence More...

    As with most medications, many doctors start you off at the lowest therapeutic dose and increase from there. For men between 18 and 64, the recommended dose for Viagra is 50 milligrams. For men 65 and older, the recommended dose is 25 milligrams. However, it may be that the dose is too low for you if it’s not improving your erectile dysfunction symptoms. Therefore, we may try increasing the dose until we find one that works well for you. Doses can go up to 100 milligrams, so we may try incrementally increasing the dose until we reach that point, depending on your unique situation.
    Drugwatch.com writers follow rigorous sourcing guidelines and cite only trustworthy sources of information, including peer-reviewed journals, court records, academic organizations, highly regarded nonprofit organizations, government reports and interviews with qualified experts. Review our editorial policy to learn more about our process for producing accurate, current and balanced content. Berman, L. (2014, June 25). The truth about erectile dysfunction. Retrieved from: https://www.foxnews.com/health/the-truth-about-erectile-dysfunction Brophy Marcus, M. (2016, March 10). First generic version of Viagra approved by FDA. Retrieved from: https://www.cbsnews.com/news/first-generic-drug-for-viagra-called-sildenafil-citrate-approved-by-fda/ FDA. (2012, August 30). FDA Drug Safety Communication: FDA recommends against use of Revatio (sildenafil) in children with pulmonary hypertension. Retrieved from: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-recommends-against-use-revatio-sildenafil-children-pulmonary FDA. (2014, March 31). FDA Drug Safety Communication: FDA clarifies Warning about Pediatric Use of Revatio (sildenafil) for Pulmonary Arterial Hypertension. Retrieved from: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-clarifies-warning-about-pediatric-use-revatio-sildenafil-pulmonary FDA. (2018). Full Prescribing Information: Revatio (sildenafil). Retrieved from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021845s018lbl.pdf FDA. (2017). Viagra – sildenafil citrate tablet, film coated: Full Prescribing Information. Retrieved from: http://labeling.pfizer.com/ShowLabeling.aspx?id=652 Brigham Health. (2020). Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION). Retrieved from: https://www.brighamandwomens.org/neurology/neuro-ophthalmology/non-arteritic-anterior-ischemic-optic-neuropathy Heid, M. (2014, October 28). The Truth about Erectile Dysfunction. Retrieved from: https://www.menshealth.com/health/a19521004/rising-erectile-dysfunction-rates/ History.com, A&E Television Networks, LLC. (2019, July 28). 1998: FDA approves Viagra. Retrieved from: http://www.history.com/this-day-in-history/fda-approves-viagra Li, W., Qureshi, A. A., Robinson, K. C., et al. (2014). Sildenafil Use and Increased Risk of Incident Melanoma in US Men: A Prospective Cohort Study. Retrieved from: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1857095 MedlinePlus, NIH. (2018, January 15). Sildenafil. Retrieved from: https://medlineplus.gov/druginfo/meds/a699015.html MedlinePlus, NIH. (2016, August 24). Sexual Problems in Men. Retrieved from: https://medlineplus.gov/sexualproblemsinmen.html MedlinePlus, NIH. (2017, January 3). Erectile Dysfunction. Retrieved from: https://medlineplus.gov/erectiledysfunction.html NIH. (2017). Erectile Dysfunction. Retrieved from: https://www.niddk.nih.gov/health-information/urologic-diseases/erectile-dysfunction NIH. (2016). Pulmonary arterial hypertension. Retrieved from: https://medlineplus.gov/genetics/condition/pulmonary-arterial-hypertension/ Pendick, D. (2014, June 5). Erectile dysfunction drugs and skin cancer – should you worry? Retrieved from: https://www.health.harvard.edu/blog/erectile-dysfunction-drugs-skin-cancer-worry-201406057197 Panchatsharam, P. K., & Zito, P. M. (2019, April 21). Physiology, Erection. Retrieved from: https://www.ncbi.nlm.nih.gov/books/NBK513278/ Loeb, S. et al. (2015). Use of Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction and Risk of Malignant Melanoma. Retrieved from: https://jamanetwork.com/journals/jama/fullarticle/2338254 Pottegård, A. et al. (2016). Use of sildenafil or other phosphodiesterase inhibitors and risk of melanoma. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046205/. Wang, J. Z. et al. (2019). No Causal Link between Phosphodiesterase Type 5 Inhibition and Melanoma. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704303/

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Sound waves directed at the penis and surrounding tissues stimulate blood flow, cellular growth and generation of new, healthy blood vessels (neovascularization). Studies show that acoustic (sound) wave therapy such as pulse therapy also provides long-term improvement of physiological mechanisms involved in erections. No side effects have been reported by men using pulse therapy for ED.5

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All authors had contributed to the data analysis, drafting, or revising the article. They gave the final approval of the manuscript to be published and agreed to be accountable for all aspects of the work.

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Several non-pharmaceutical methods may help increase blood flow to the penis naturally. You can try these alone or in conjunction with medication.

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