All authors had contributed to the data analysis, drafting, or revising the article. They gave the final approval of the manuscript to be published and agreed to be accountable for all aspects of the work.
"No-nose" bike seats protect against genital numbness and sexual dysfunction, according to the National Institute for Occupational Safety and Health. .
"Drugwatch opened my eyes to the realities of big pharmacy. Having a family member with major depression and anxiety, I was looking for information on her medications. I found information that was very helpful, that her psychiatrist never told her." Marianne Zahren Patient’s Family Member
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
If you smoke, talk to your doctor about quitting and whether prescription aids can help you.
Impotence, also called erectile dysfunction (ED), can be a very frustrating problem. Some men are able to achieve an erection but are not able to maintain one. Others are not able to achieve one at all. Causes of impotence can be both physiological (affecting mostly the body and organs) or psychological (affecting the mind). Luckily, there are natural remedies for impotence you can try.
Sildenafil is cleared predominantly by the CYP3A4 (major route) and CYP2C9 (minor route) hepatic microsomal isoenzymes. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% of the parent drug. Plasma concentrations of this metabolite are approximately 40% of those seen for sildenafil, so that the metabolite accounts for about 20% of sildenafil's pharmacologic effects.
Medical News Today states that performing Kegel exercises may strengthen a man’s pelvic region and help with symptoms relating to ED. The pelvic floor can increase rigidity during erections. This muscle keeps blood from leaving the penis by pressing on a key vein. Kegel exercises can strengthen these muscles and can possibly lead to improved sexual performance.
Seeing a psychologist or other mental health professional could help improve your ED symptoms. You may want to bring your partner along for counseling sessions to discuss ways to encourage each other. If you don’t know where to start to look for counseling, ask your doctor or urologist for a specific recommendation.
Medicine such as sildenafil (sold as Viagra) is also often used by doctors to treat erectile dysfunction. It's also available from pharmacies.
Meanwhile, PDE-5 (phosphodiesterase-5) is a chemical that the body releases to signal that it’s time for the erection to end. PDE-5 inhibitors slow the activity of PDE-5, allowing the NO activity to continue, bringing forth an erection.
Viagra and the other phosphodiesterase 5 inhibitors are great drugs for the right men. They may induce an erection in over 80 percent of men with ED. Many millions of men have used these drugs safely and appropriately.
Tags: elderly, erectile dysfunction, impotence, male, Men's Health, older adults, senior
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Espinosa says it can ease symptoms of exhaustion and ED. And it’s less likely to leave you feeling wired than some other products. The side effects are minimal, he says, both in his experience and in the studies he’s seen.
If it happens more often, it may be caused by physical health or emotional problems. Non-urgent advice: See a GP or go to a sexual health clinic if:
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