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Erectile Dysfunction (ED), also known as impotence, is a type of male sexual dysfunction characterized by the inability to maintain an erection long enough and firm enough for sexual intercourse.

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This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Note that the numbers in parentheses (1, 2, etc.) are clickable links to medically peer-reviewed studies.
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In the present study, the recreational use of sildenafil was also more prevalent in participants who had multiple sexual partners. Similar findings were also reported in a study conducted in Brazil (6), and this could be because men with multiple sexual partners may be attempting to impress their partners with prolonged sexual periods (7, 8). It could also be attributed to a low level of self-esteem in men who had multiple sexual partners.

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Renal Impairment: In volunteers with mild (CLcr=50-80 mL/min) and moderate (CLcr=30-49 mL/min) renal impairment, the pharmacokinetics of a single oral dose of VIAGRA (50 mg) were not altered. In volunteers with severe (CLcr < 30 mL/min) renal impairment, sildenafil clearance was reduced, resulting in approximately doubling of AUC and Cmax compared to age-matched volunteers with no renal impairment [see DOSAGE AND ADMINISTRATION, and Use In Specific Populations].
Healthy elderly volunteers (65 years or over) had a reduced clearance of sildenafil resulting in approximately 84% and 107% higher plasma AUC values of sildenafil and its active N-desmethyl metabolite, respectively, compared to those seen in healthy young volunteers (18-45 years) [see CLINICAL PHARMACOLOGY]. Due to age-differences in plasma protein binding, the corresponding increase in the AUC of free (unbound) sildenafil and its active N-desmethyl metabolite were 45% and 57%, respectively [see CLINICAL PHARMACOLOGY].

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Horny Goat Weed: Extracts from the leaves of this herb have long been used as an ED remedy in traditional Chinese medicine. At least one study on rats showed promise, but it has yet to be tested on people.

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The editor and reviewer's affiliations are the latest provided on their Loop research profiles and may not reflect their situation at the time of review. TABLE OF CONTENTS Abstract Introduction Methods Results Discussion Conclusion Data Availability Statement Ethics Statement Author Contributions Conflict of Interest Publisher's Note Acknowledgments References People also looked at ORIGINAL RESEARCH article https://doi.org/10.3389/fmed.2021.665247 The Weekend Drug; Recreational Use of Sildenafil Citrate and Concomitant Factors: A Cross-Sectional Study Berhanemeskel Weldegerima Atsbeha1, Beza Tefera Kebede2, Biruktawit Shewafera Birhanu2, Dawit Kumilachew Yimenu1*, Wudneh Simegn Belay1 and Chilot Abiyu Demeke1 1Department of Pharmaceutics and Social Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia 2College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia

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    Hemic and Lymphatic: vaso-occlusive crisis: In a small, prematurely terminated study of REVATIO (sildenafil) in patients with pulmonary arterial hypertension (PAH) secondary to sickle cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported in patients who received sildenafil than in those randomized to placebo. The clinical relevance of this finding to men treated with VIAGRA for ED is not known.

    Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with VIAGRA (50 mg) to healthy volunteers.
    Here are some home/natural remedies which can be considered as a healthy alternative to viagra and will give your erection a boost: Zee News App: Read latest news of India and world, bollywood news, business updates, cricket scores, etc. Download the Zee news app now to keep up with daily breaking news and live news event coverage. ViagraNatural remediesAlternative to viagraErectile dysfunctionsexual desireImpotence in menPomegranate juiceGinsengAshwagandhaDrumsticksJeeraGinkgo bilobaHorny Goat WeedSaw palmettolibido Seven reasons why you should eat curd everyday! Comments - Join the Discussion How a Chinese Railway can decide the next President of Kenya | Zee English News Latest: Why Elon Musk sold 7.92 million shares of Tesla, major one since April? | Zee English News Azadi Ka Amrit Mahotsav: Indian diaspora's major role for securing New Delhi's interests globally Azadi Ka Amrit Mahotsav: India's music connected had several phases since Independence Azadi Ka Amrit Mahotsav: Expansion of liberalisation created alot of business leaders Azadi Ka Amrit Mahotsav: India became a manufacturing hub after Make in India What did the veteran leaders say after oath ceremony of new government in Bihar? India News| State News| World News| Sports News| Cricket News| Business News| Entertainment News| Technology News| Science News| Health News| Blogs| Photos| Video| zee media websites hindi news bengali news marathi news tamil news malayalam news Gujarati News Telugu News Kannada News zeebiz wion dna Investor Info Advertise With Us © 1998-2022 India Dot Com Private Limited. All rights reserved. |

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    All of the ED cases have one thing in common: they result in either decreased blood flow, or atherosclerosis (hardening of the arteries).

    When VIAGRA 100 mg oral was co-administered with amlodipine, 5 mg or 10 mg oral, to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic.
    Vasculogenic ED, or ED caused by decreased blood flow, is thought to be the main contributor to ED in most men and should prompt age related ED treatment concerns for physicians. Main contributors to vasculogenic ED include: Aging Blood medications Stress Anxiety Depression Trauma Obesity Lack of mobility Diabetes Smoking Drug or alcohol use Erectile Dysfunction Treatment Options in Oakdale, MN

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    Tom and Rachael Sullivan share PCOS-friendly meals on their Instagram account and have marked each week of Rachael's pregnancy with adorable food-themed photos.

    There are many herbal remedies which are good for the improvement in erectile dysfunction, but most of them have little effect and have side effects. There are two herbal remedies which have shown that erectile dysfunction can be gone if you take them, which are red ginseng and pomegranate juice. Ginseng will increase nitric oxide production, which leads to improved blood flow. In the case of pomegranate juice, it acts an antioxidant and helps to prevent atherosclerosis. You should consult with your doctor before taking any supplements as they can interfere with some other medication you are taking.
    A wide variety of treatments for ED are now available. Remember, however, that not all men are entitled to treatment through the NHS.

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    It’s important to discuss your plans with your doctor before you try a natural or alternative approach.

    Tell all your healthcare providers that you take VIAGRA. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took VIAGRA.
    Psychological and emotional disorders, such as anxiety, depression and stress, as well as certain lifestyle choices, such as an unhealthy diet, lack of exercise, drinking in excess and smoking, can cause or exacerbate ED. ED can also be a potential side effect when taking certain medications, including those used to treat blood pressure, allergies, depression and ulcers.

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In patients who either fail to respond to first or second-line therapy, or are not interested in the conservative therapies, penile prosthesis implantation is available. Malleable and rigid implants were available for many years, but in 1973 the world of penile prosthetics took a giant leap forward with the advent of the inflatable penile implant. Most implants done nowadays are of the inflatable variety. Adverse events including malfunction and infection are rare, and patient satisfaction is very high.45

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Medscape: "Tobacco Education: Emphasizing Impotence as a Consequence of Smoking."

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Stem cell intracavernosal therapy and platelet‐rich plasma (PRP) therapy are both considered investigational.

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Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having pulmonary arterial hypertension (PAH) during pregnancy may cause complications such as heart failure, stroke, or medical problems in both mother and baby. The benefit of treating PAH with Revatio may outweigh any risks to the baby.

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